Structure of PDB 7unr Chain Q Binding Site BS02

Receptor Information

>7unr Chain Q (length=115) Species: 208964 (Pseudomonas aeruginosa PAO1)

SVKKETRLRRARKARLKMRELETVRLCVYRSSQHIYAQVIAADGGKVLAS
ASTLDKDLREGATGNIDAAKKVGQLVAERAKAAGVTQVAFDRSGFKYHGR
VKALADAAREGGLEF

Ligand information

>7unr Chain B (length=117)

gcuugacgaucauagagcguuggaaccaccugaucccuucccgaacucag
aagugaaacgacgcaucgccgaugguaguguggggucuccccaugugaga
guaggucaucgucaagc

<<<<<<<<<<....<<<<<<<<....<<<<<<<.............>>>>
..>>>...>>>>>>.>><<<.......<<<<<<<<...>>>>>>>>....
...>>>.>>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7unr Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): S2 K4 R16 R20 R26 Y30 R31 S32 S33 Q34 H35 Y37 I41 G45 V48 S51 K57 N66 I67 H99 G100 R101
• Binding residue (residue number reindexed from 1): S1 K3 R15 R19 R25 Y29 R30 S31 S32 Q33 H34 Y36 I40 G44 V47 S50 K56 N65 I66 H98 G99 R100

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7unr, PDBe:7unr, PDBj:7unr
• PDBsum: 7unr
• UniProt: Q9HWF1|RL18_PSEAE Large ribosomal subunit protein uL18 (Gene Name=rplR)