Structure of PDB 7s0s Chain Q Binding Site BS02
Receptor Information
>7s0s Chain Q (length=126) Species:
1772
(Mycolicibacterium smegmatis) [
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AHKPVGQNISEVRRNARLRRHARLRKKVAGTAEVPRLVVNRSARHIHVQL
VNDLNGTTLAAASSIEADVRAIDGDKKAHSVRVGQLIAERAKAAGVETVV
FDRGGYTYGGRIAALADAAREAGLKF
Ligand information
>7s0s Chain i (length=118) [
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guuacggcgguccauagcggcagggaaacgcccggucccaucccgaaccc
ggaagcuaagccugccagcgccgaugauacuacccauccggguggaaaag
uaggacaccgccgaacac
<<<.<<<<<<<.....<<<<<<<<.....<<<<<...............>
>>..>>....>>>>>>.>>.<<.......<<<<<<....>>>>>>.....
..>>..>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB
7s0s
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Resolution
3.05 Å
Binding residue
(original residue number in PDB)
N9 S11 E12 R14 R15 H22 R26 R37 N41 S43 H46 H48 Q50 T58 I66 R71 D76 K77 K78 T108 G111 R112
Binding residue
(residue number reindexed from 1)
N8 S10 E11 R13 R14 H21 R25 R36 N40 S42 H45 H47 Q49 T57 I65 R70 D75 K76 K77 T107 G110 R111
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:7s0s
,
PDBe:7s0s
,
PDBj:7s0s
PDBsum
7s0s
PubMed
35357969
UniProt
A0QSG5
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