Structure of PDB 7q0f Chain Q Binding Site BS02

Receptor Information
>7q0f Chain Q (length=118) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKQFSFKGVDLKDLVEMPTEEFTKLCGARVRRRFSRGLDSKPMGLIKKLR
AARAATEPNERPAVVKTHLRNMIVVPEMIGSVVGVYNGKVFNTVEIKPEM
VGHYLGEFSITYTPVRHG
Ligand information
>7q0f Chain A (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaauuugaugauucauaauaacuuuucgaaucgcauggcc
uugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaugg
uaggauaguggccuaccaugguuucaacggguaacggggaauaaggguuc
gauuccggagagggagccugagaaacggcuaccacauccaaggaaggcag
caggcgcgcaaauuacccaaucccgacacggggagguagugacaauaaau
aacgauacagguuguaauuggaaugaguacaauguaaauaccuuaacgag
gaacaauuggagggcaagucuggugccagcagccgcgguaauuccagcuc
caaaagcguauauuaaaguuguugcaguuaaaaagcucguaguugaaccu
ugggcuuggcuggccgguccuggacccagccgagccuuuccuucuggcca
ggacuuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucga
auauauuagcauggaauaauagaauaggacguuaugguucuauuuuguug
guuucuaggaccaucguaaugauuaauagggacggucggggguaucagua
uucaguugucagaggugaaauucuuggauuuacugaagacuaacuacugc
gaaagcauuuaccaaggacguuuucauuaaucaagaacgaaaguuagggg
aucgaagaugaucagauaccgucguagucuuaaccauaaacuaugccgac
uagggaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaa
aucaaagucuuuggguucuggggggaguauggucgcaaggcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaacucaccagguccagacacaauaaggauugacag
auugagagcucuuucuugauuuugugggugguggugcauggccguucuua
guugguggagugauuugucugcuuaauugcgauaacgaacgagaccuuaa
ccuacuaaauagugcugcuagcauuugcugguauagucacuucuuagagg
gacuaucgauuucaagucgauggaaguuugaggcaauaacaggucuguga
ugcccuuagacguucugggccgcacgcgcgcuacacugacggagccagcg
aguauaagccuuggccgagaggucugggaaaucuugugaaacuccgucgu
gcuggggauagagcauuguaauuguugcucuucaacgaggaauuccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaauggcuuagugaggccuccggauugg
uuuagggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaa
gucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<....................>>>>>>.....>...<<<<..<<<.
....>>>.>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<
<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....>>>>
....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>
>>>>>.........<<<....<<<<...>>>>..>>>..>....>.>...
..<<<<...<..>...>>>>......<<..<...........>..>>...
......<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>>.........<<<((.....<.<<...<<<.<<...
.<<<<<<<<<<<<............>>>>>>>>>>>>....<<<<<..>>
>>>...<<<<<.<<.......<<...<.......>..<<<....>>>...
.>>......>>.>>..>>>.........<<<..<<<<<<<<<........
.....>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..
<<<<<<.<...<<<......>>>......>.>>>>>>..>>.......<<
....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<.
..<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<
.<<<..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..)
)>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<
<........>>..........<<<<<.<....<<<<<........<<.<<
<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....
<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.
<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>
....<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>
>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<<<<<<......
<<......<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
.........<<<<<<..........>>>>>>..........>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<
.........>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...
>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7q0f E-site drug specificity of the human pathogen Candida albicans ribosome.
Resolution2.64 Å
Binding residue
(original residue number in PDB)		K18 G38 A39 R40 R42 R43 R44 R47 K59 K77 H79 R81 N82 Y97 N98 G99 K100 F102 Y115 G117 T122 Y123 T124 V126 R127 H128
Binding residue
(residue number reindexed from 1)		K7 G27 A28 R29 R31 R32 R33 R36 K48 K66 H68 R70 N71 Y86 N87 G88 K89 F91 Y104 G106 T111 Y112 T113 V115 R116 H117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7q0f, PDBe:7q0f, PDBj:7q0f
PDBsum7q0f
PubMed35613268
UniProtA0A1D8PK22|RS15_CANAL Small ribosomal subunit protein uS19 (Gene Name=RPS15)

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