Structure of PDB 6rwe Chain Q Binding Site BS02

Receptor Information
>6rwe Chain Q (length=477) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDEDLGAGVI
TRRLNLTTNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLK
SFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQL
HMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQ
LPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKL
VMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRV
LSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVV
YPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTDQKIARRKLYKIFPLDRE
ANHDGEFNDSTHQLTFIEDLQERYAKQTPFFPPARKEAIGRLLTHIASQL
LVDFAISKEQLKDCISRIKNACLHRMN
Ligand information
>6rwe Chain U (length=45) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tggagtacaagtgtgaggaaaagtagttggcggaagtaaagcagt
Receptor-Ligand Complex Structure
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PDB6rwe Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		N209 V212 S213 E216 S218 R293 H294 R504
Binding residue
(residue number reindexed from 1)		N203 V206 S207 E210 S212 R287 H288 R467
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rwe, PDBe:6rwe, PDBj:6rwe
PDBsum6rwe
PubMed31804486
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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