Structure of PDB 3zha Chain Q Binding Site BS02

Receptor Information
>3zha Chain Q (length=365) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNNVTWKLGSRLYGPS
SVSFAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEV
TKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMH
RTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKE
QLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLS
RMSGKKDLYLASVFHATAFEWDTEGNPFDQDSPKLFYADHPFIFLVRDTQ
SGSLLFIGRLVRPKG
Ligand information
>3zha Chain T (length=16) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PPGPPGPTGPRGPPGP
Receptor-Ligand Complex Structure
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PDB3zha Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		M218 R222 M225 H238 S305 Y383 D385
Binding residue
(residue number reindexed from 1)		M180 R184 M187 H200 S267 Y337 D339
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005518 collagen binding
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3zha, PDBe:3zha, PDBj:3zha
PDBsum3zha
PubMed22847422
UniProtC7C419

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