Structure of PDB 3jcs Chain Q Binding Site BS02

Receptor Information
>3jcs Chain Q (length=156) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSLKLQARLASSILGCGRARVWLDPNEAVEIQNANSRKSVRKLIKDGFII
RKPVKVHSRARWRKMKEAKDMGRHNGVGRREGSREARMPSKELWMRRLRI
LRRLLRKYRADKKIDRHVYRDLYVRAKGNVFRNKRNLVEHIHKIKNEKKK
ERQLAE
Ligand information
>3jcs Chain 2 (length=1119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccacucagaacu
gcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaugc
auccaagugguguauaucgcaaacugauuucugcccagugcucugaaugu
caacgugacgagauucaccgacgcgcggguaaacggcgggagacucucuu
aagguagccaaaugccucgucuuccaauuagagacgcgcaugaauggauu
aaugagauucccucugucccgaguuacuaucuagcgaaacgacagucaag
ggaacggacuugaagggcuaagcggggaaagaagacccuguugaguuuga
cuccagucuggcucugugcggcgacaucugagguguaguauagguggaag
cgcaagcgcaaaugaaauaccaccacucggaaguugcuucacuuaucgaa
ugaagagaccaauggguuuagcguagucuggcuaugcaccgucuagguuu
gggaguaauuuuauggcggggugugcuugggcgugacucguggguaccca
accgugcuguaaacugaaccaacgggauugccucgugcaguuccgggucu
uguuucgagacaucugccagauggggaguuuggcugcggcuaucuguuac
acgacaacgcagguguccuaaggcgagcucagugggaacaaucucacgua
gaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaaucga
gacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauaccag
aggugucagaauaauuaccacagggauaacuggcuuguggcggccaagcg
auagcgacgucgcuuuuugauccuucgaugucggcucuuccuaaccuagc
gccgcagaagacgcuaaggguuggauuguucacccacugacagggaacgu
gagcuggguuuagaccgucgugagacagguugguuuuacccuacuuagcu
ggaaauugcgagaaaaaga
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<...............<<<<
<.....<..>......>>>>><<.<<<<<<.<......>..>>>>>>.>>
..........<<<<<<<<<..<<<.........>>>..<<<<<<<....<
<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<<
....<<<<......>>>>....>>..>>>>..>>>>>.............
......<...........<<<<<.......>>>>>.....>.....>>..
..>>.>>>>>>>.....>>.>>>>>>>>.>>>>............<<<<<
........>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<
<<<<.<<<<<<<...<<<.<<<<<<.<<<.....................
............................>>>.>>>>>>.>>>...<<<<<
.....<<<.....<<.....<<<<<<<...>>>>>>>....>>.....<.
..<..................<<<<<<..>>>>>>...............
..>..>................<<<<<<<<.......>>>>>>>>..>>>
...>>>>>.......>>>>>>>..>>>>>..<<<....>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<....>>>>>>...
..<<......>>....>>>>>>>...<<..<<<<<<.......>>>>>>.
>>.<<<....>>>.>>........<<<<<<..<<<.......>>>..>>>
>>>.........>>>>..>>>>>>.......<<.<...<.<.<.....<.
...>.....>.>.>....>.>.>.......<<<<<.<<<<<<..<<<<<<
<.<......>.>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>>>>>
...................
Receptor-Ligand Complex Structure
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PDB3jcs 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C17 R19 R21 V55 H58 R60 W63 D71 G77 V78 G79 R81 E82 G83 S84 R85 R88 K135
Binding residue
(residue number reindexed from 1)		C16 R18 R20 V54 H57 R59 W62 D70 G76 V77 G78 R80 E81 G82 S83 R84 R87 K134
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jcs, PDBe:3jcs, PDBj:3jcs
PDBsum3jcs
PubMed27373148
UniProtE9B8Q2

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