Structure of PDB 2pmz Chain Q Binding Site BS02

Receptor Information
>2pmz Chain Q (length=776) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNIKGIKFGILSPDEIRKMSVTAIITPMDPRLGVIEPGQKCPTCGNTLGN
CPGHFGHIELVRPVIHVGLVKHIYEFLKAKLTPSDIRERLEKIPDSDVEI
LGYDPTTSRPEWMILTVLPVPPITIRPSEDDLTHKLVDIVRINERLKESI
DAGAPQLIIEDLWDLLQYHVATYFDNEIPGLPPSKHRSGRPLRTLAQRLK
GKEGRFRGNLSGKRVDFSSRTVISPDPNISIDEVGVPEIIAKTLTVPERI
TPWNIEKLRQFVINGPDKWPGANYVIRPDGRRIDLRYVKDRKELASTLAP
GYIIERHLIDGDIVLFNRQPSLHRISMMAHRVRVLKGLTFRLNLLVCPPY
NADFDGDEMNLHVPQSEEAIAEAKEIMLVHKNIITPRYGGPIIGAAQDYI
SGAYLLTVKTTLLTKEEAQQILGVADVKIDLGEPAILAPREYYTGKQVIS
AFLPKDFNFHGQANVSSGPRLCKNEDCPHDSYVVIKNGILLEGVFDKKAI
GNQQPESILHWLIKEYSDEYGKWLMDNLFRVFIRFVELQGFTMRLEDVSL
GDDVKKEIYNEIDRAKVEVDNLIQKYKNGELEPIPGRTLEESLENYILDT
LDKLRSTAGDIASKYLDPFNFAYVMARTGARGSVLNITQMAAMLGQQSVR
GERIKRGYMTRTLPHFKPYDISPEARGFIYSSFRTGLKPTELFFHAAGGR
EGLVDTAVRTSQSGYMQRRLINALSDLRAEYDGTVRSLYGEVVQVAYGDD
GVFPMYSAHGKTVDVNRIFERVVGWK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2pmz Chain Q Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2pmz The X-ray crystal structure of RNA polymerase from Archaea
Resolution3.4 Å
Binding residue
(original residue number in PDB)		D456 D458 D460
Binding residue
(residue number reindexed from 1)		D353 D355 D357
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2pmz, PDBe:2pmz, PDBj:2pmz
PDBsum2pmz
PubMed18235446
UniProtQ980R2|RPO1N_SACS2 DNA-directed RNA polymerase subunit Rpo1N (Gene Name=rpo1N)

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