Structure of PDB 8ipb Chain PA Binding Site BS02

Receptor Information
>8ipb Chain PA (length=130) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKRNPRVTSSRRKCRKAHFTAPSSVRRVLMSAALSSELRHKYNVRSIPIR
KDDEVQVVRGTYKGREGKVVQVYRRRWVIHVERITREKVNGSTVNVGIHP
SKVIVTKLKLDKDRKALLDRKARGRAADKA
Ligand information
>8ipb Chain SB (length=160) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucucggcaacggauaucucggcucucgcaucgaugaagaacguagc
gaaaugcgauaccuggugugaauugcagaaucccgugaaccaucgagucu
uugaacgcaaguugcgcccgaggccauccggccgagggcacgccugccug
ggcgucacgc
.........................................<<<<<<.((
.....>>>....<<<<<<<.....))............>.>>>>.>>..>
>>....<<.....>><<<<..<<<<....>>>>..>>>>...........
..........
Receptor-Ligand Complex Structure
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PDB8ipb Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R11 R12 R15 K16 F19 P22 S23 S24 R27 R50 K51 Q71 V72 Y73 R74 R75 L110 D111 K112 D113 K115 R120
Binding residue
(residue number reindexed from 1)		R11 R12 R15 K16 F19 P22 S23 S24 R27 R50 K51 Q71 V72 Y73 R74 R75 L110 D111 K112 D113 K115 R120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ipb, PDBe:8ipb, PDBj:8ipb
PDBsum8ipb
PubMed38267667
UniProtA0A3B6GQI2

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