Structure of PDB 8kab Chain P Binding Site BS02

Receptor Information
>8kab Chain P (length=126) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHKPVGQNISEVRRNARLRRHARLRKKVAGTAEVPRLVVNRSARHIHVQL
VNDLNGTTLAAASSIEADVRAIDGDKKAHSVRVGQLIAERAKAAGVETVV
FDRGGYTYGGRIAALADAAREAGLKF
Ligand information
>8kab Chain B (length=118) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuacggcgguccauagcggcagggaaacgcccggucccaucccgaaccc
ggaagcuaagccugccagcgccgaugauacuacccauccggguggaaaag
uaggacaccgccgaacac
<<<.<<<<<<<.....<<<<<<<<.....<<<<<...............>
>>..>>....>>>>>>.>>.<<.......<<<<<<....>>>>>>.....
..>>..>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8kab Cryo-EM structures reveal the molecular mechanism of HflX-mediated erythromycin resistance in mycobacteria.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N9 S11 E12 R14 R15 R18 H22 R26 R37 R42 S43 R45 H48 Q50 G57 T58 T59 R71 D76 K77 K78 T108 G111 R112
Binding residue
(residue number reindexed from 1)		N8 S10 E11 R13 R14 R17 H21 R25 R36 R41 S42 R44 H47 Q49 G56 T57 T58 R70 D75 K76 K77 T107 G110 R111
Gene Ontology
Molecular Function
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8kab, PDBe:8kab, PDBj:8kab
PDBsum8kab
PubMed39029461
UniProtA0QSG5

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