Structure of PDB 8ifg Chain P Binding Site BS02

Receptor Information
>8ifg Chain P (length=239) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMVDVWMQLCTYIDSHNPIQFHLPHSISSFFRGVGSGVMGEYIETDVLKH
LERDPLLLKSKSGTPILCFRCHKSALVSQSILACDYCNSYWHPDCLNPPL
ATLPSNLRKWKCPNHSDHVTPRYRLPEKAKVIRVGLPRGFKNKGNIVIDE
NEKPFKLNFLEQIRDNVINLRKMVEQDEQLCIETFSKFDFYATRDCELPL
RILCDVANDNLENDDYVLALRDLLRISKWDPNQPVPAPF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ifg Chain P Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ifg Class I histone deacetylase complex: Structure and functional correlates.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C425 C428 C453 H456
Binding residue
(residue number reindexed from 1)		C84 C87 C112 H115
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0060090 molecular adaptor activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0045815 transcription initiation-coupled chromatin remodeling
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0032221 Rpd3S complex
GO:0032991 protein-containing complex
GO:0072686 mitotic spindle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ifg, PDBe:8ifg, PDBj:8ifg
PDBsum8ifg
PubMed37459529
UniProtQ09698|YA27_SCHPO Uncharacterized protein C2F7.07c (Gene Name=SPAC2F7.07c)

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