Structure of PDB 8a98 Chain P Binding Site BS02

Receptor Information
>8a98 Chain P (length=197) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVDLTGISKKSRVIRHHTYSTNPYIKLLIKLYKFLAKRTSSGFNKVVYQR
LIKSRSNRAPISLSRIAVVMKRKAVFTAKSKAAPIAVVVGDVLDDVRMAR
IPAMRVCALRFSKSARQSIVAAGGECLTFDQLAMIAPTGKNTYLLRGRKS
GRESVRHFGASGVPGSHSKPYATNRGKETKRGRRTGRSYKRKAFRHV
Ligand information
>8a98 Chain 2 (length=1047) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguaaacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaacacaaauugccaacuc
agaacugcuuacggcggggaauccaacuguauaauuaaaacauagguuug
ugaugcauccaagugguguauaucgcaaacugauuucugcccagugcucu
gaaugucaacgugacgagauucaccgacgcgcggguaaacggcgggagua
auaugacucucuuaagguagccaaaugccucgucuuccaauuagagacgc
gcaugaauggauuaaugagauucccucugucccgaguuacuaucuagcga
aacgacagucaagggaacggacuugaagggcuaagcggggaaagaagacc
cuguugaguuugacuccagucuggcucugugcggcgacauguugcuucac
uuaucgaaugaagagaccaaugggauuagcguagucuucgggcuaugcac
cgucuagguuccaaccgugcuguaaacugaaccaacgggauccggagucu
uguuucgagacaucugccagauggggaguuuggcuggggcggcauaucug
uuacacgacaacgcagguguccuaaggcgagcucagugggaaaucucacg
uagaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaauc
gagacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauacc
agaggugucagaauaauuaccacagggauaacuggcuuuggcggccaagu
cgcugauccuucgaugucggcucuuccuaaccuagcgcgacgcuaagggu
uggauuguucacccacugacagggaacgugagcuggguuuagaccgucgu
gagacagguugguuuuacccuacuuagcuggaaauugcgagaaaaagauu
auccgugcaaagcggagcgguggguaguacuugguacgcucaucacc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<......>>>>>..>>>
>>>.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<
<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.
<...<<....<<<<......>>>>....>>.>>>>>..>>>>>....<..
.......>...........<...........<<<<<.......>>>>>..
...>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>....
........<<<<<........>>>>>..<<<<<<<..<<<.<<......<
<<<.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<..>>>>>>.>>>
...<<<<<.....<<<<....<<.....<<<<<<<<<..>>>>>>>>>.>
>.....<<<<..>>>>...................<<<...>>>..>>>>
...>>>>>.......>>>>>>>..>>>>>...<<<.....>>>..<<<<<
<...........>>>>>>..<<...<<<<<<<...<<<<<<..>>>>>>.
....<<......>>....>>>>>>>...<<...<<<<<.......>>>>>
..>>.<<<....>>>.>>.........<<<<<..<<<.......>>>..>
>>>>..........>>>>..>>>>>>.......<<.<......<......
>...>..>>.......<<<<<.<<<<<<..<<<<<<<...>>>>..>>>.
<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....>>..>>>.>>>>>>>.....................
.<.<.......>.>..<.<<<<<<<.<<<<...>>>>>>>>>>>.>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a98 CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Resolution2.46 Å
Binding residue
(original residue number in PDB)		P165 R185 R188 S189 K191 H197
Binding residue
(residue number reindexed from 1)		P164 R184 R187 S188 K190 H196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a98, PDBe:8a98, PDBj:8a98
PDBsum8a98
PubMed38722744
UniProtQ4QG98|RL18_LEIMA Large ribosomal subunit protein eL18 (Gene Name=RPL18-A)

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