Structure of PDB 7ux9 Chain P Binding Site BS02

Receptor Information
>7ux9 Chain P (length=468) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQLKSYQLKGVKWLISLWQNGLNGILADQMGLGKTIQTIGFLSHLKGNGL
DGPYLVIAPLSTLSNWFNEIARFTPSINAIIYHGDKNQRDELRRKHMPKT
VGPKFPIVITSYEVAMNDAKRILRHYPWKYVVIDEGHRLKNHKCKLLREL
KHLKMDNKLLLTGTPLQNNLSELWSLLNFILPDIFTSHDEFESWFDFSEK
NKNEATKEEEEKRRAQVVSKLHGILRPFILRRMKCDRKKEIIMYATMTDH
QKKFQEHLVNNTLEAHLGENAIRGQGWKGKLNNLVIQLRKNCNHPDLLQG
QIDGSYLYPPVEEIVGQCGKFRLLERLLVRLFANNHKVLIFSQWTKLLDI
MDYYFSEKGFEVCRIDGSVKLDERRRQIKDFSDEKSSCSIFLLSTRAGGL
GINLTAADTCILYDSDWNPQMDLQAMDRCHRIGQTKPVHVYRLSTAQSIE
TRVLKRAYSKLKLEHVVI
Ligand information
>7ux9 Chain Z (length=141) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atgtatatatgtgacacgtgcctggagactagggagtaatccccttggcg
gttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagct
gtctacgaccaattgagcggcctcggcaccgggattctcca
Receptor-Ligand Complex Structure
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PDB7ux9 Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
K285 E312 N487 K495 W549 T550 K551 R601 A602
Binding residue
(residue number reindexed from 1)
K86 E113 N282 K290 W344 T345 K346 R396 A397
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006346 DNA methylation-dependent heterochromatin formation
GO:0009294 DNA-mediated transformation
GO:0031507 heterochromatin formation
GO:0032197 retrotransposition
GO:0032508 DNA duplex unwinding
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ux9, PDBe:7ux9, PDBj:7ux9
PDBsum7ux9
PubMed37643610
UniProtQ9XFH4|DDM1_ARATH ATP-dependent DNA helicase DDM1 (Gene Name=DDM1)

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