Structure of PDB 5w66 Chain P Binding Site BS02

Receptor Information
>5w66 Chain P (length=387) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLIGHEAKLLFLKSFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKT
INDQPQEELKLQLHMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYF
QASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFF
NSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDER
HTGRVSNHAELRVLSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTT
TSESIGRNIVKVVYPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTQTSME
MTIDQKIARRKLYKIFPLDREDTHQLTFIEDLQERYAKQTPFFPPARKEA
IGRLLTHIASQLLVDFAISKEQLKDCISRIKNACLHR
Ligand information
>5w66 Chain T (length=54) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtcttcaactgctttcgcatgaagtacctcccaactacttttcctcaca
cttg
Receptor-Ligand Complex Structure
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PDB5w66 Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		L152 K153 L154 Q155 Y210 G224 N228 R293 H294 T295
Binding residue
(residue number reindexed from 1)		L59 K60 L61 Q62 Y117 G131 N135 R200 H201 T202
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5w66, PDBe:5w66, PDBj:5w66
PDBsum5w66
PubMed28623663
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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