Structure of PDB 5w5y Chain P Binding Site BS02

Receptor Information
>5w5y Chain P (length=387) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLIGHEAKLLFLKSFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKT
INDQPQEELKLQLHMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYF
QASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFF
NSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDER
HTGRVSNHAELRVLSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTT
TSESIGRNIVKVVYPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTQTSME
MTIDQKIARRKLYKIFPLDREDTHQLTFIEDLQERYAKQTPFFPPARKEA
IGRLLTHIASQLLVDFAISKEQLKDCISRIKNACLHR
Ligand information
>5w5y Chain T (length=54) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtcttcaactgctttcgcatgaagtacctcccaactacttttcctcaca
cttg
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5w5y Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		L152 K153 L154 Q155 H157 Y210 Q225 N228 K229 H294
Binding residue
(residue number reindexed from 1)		L59 K60 L61 Q62 H64 Y117 Q132 N135 K136 H201
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5w5y, PDBe:5w5y, PDBj:5w5y
PDBsum5w5y
PubMed28623663
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

[Back to BioLiP]