Structure of PDB 5t2a Chain P Binding Site BS02

Receptor Information
>5t2a Chain P (length=154) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THYSRKPQVSSKSAKAKVSDLRCHYKNTFETANVINGMPLRKAQQLYRQV
LAKTRCIPFKRYNGKIGRTAQAKEWGQTKGRWPRKSVVAMMSLLKNAEAN
AIEKGLDPNQMVIKHVQVDQAARMRRRTYRAHGRITPYMCSPCHVQLFMS
EKKE
Ligand information
>5t2a Chain B (length=1064) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccaacucagaac
ugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaug
cauccaagugguguauaucgcaaacugauuucugcccagugcucugaaug
ucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacuau
gacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgcau
gaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaacg
acagucaagggaacggacuugaagggcuaagcggggaaagaagacccugu
ugaguuugacuccagucuggcucugugcggcgacguugcuucacuuaucg
aaugaagagaccaaugggcgugcuguaaacugaaccaacggguccggagu
cuuguuucgagacaucugccagauggggaguuuggcuggggcggcauauc
uguuacacgacaacgcagguguccuaaggcgagcucagugggaacagaaa
ucucacguagaacacaagcguaaaagcuugcuugauuaacgauuuccagu
acgaaucgagacugcgaaagcaaggccagcgauccuuugcgaagaauagg
aaauaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuguggcggccaagcguucauagcgacgucgcuuuuugauccuu
cgaugucggcucuuccuaaccuagcgccgcagaagacgcuaaggguugga
uuguucacccacugacagggaacgugagcuggguuuagaccgucgugaga
cagguugguuuuacccuacuuagcuggaaauugcgagaaaagauuauccg
cgcaaagcggaggcaguccgucugggucugccguucgguggcaugugcuu
ggcgcugccaucuc
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<.........<.....<<<<
<...............>>>>><<.<<<<<<<<<<..>>>>..>>>>>>.>
>..........<<<<<<<<<..<<<.........>>>..<<<<<<<....
<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<
<....<<<<......>>>>....>>..>>>>..>>>>><<<<<<......
.>>>>>>........<...........<<<<<.......>>>>>.....>
.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>........
....<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<<.
<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<..>>>>>.>>>...<<<
<<.....<<<<...........................<<<..>>>..>>
>>...>>>>>.......>>>>>>>..>>>>>...<<<.....>>>..<<<
<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......
>>>>>>.....<<......>>....>>>>>>>...<<...<<<<<.....
..>>>>>..>>.<<<....>>>.>>........<<<<<<...........
...<<<<.......>>>>.>>>>>>.........>>>>..>>>>>>....
...<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>..
.....<<<<<.<<<<<<..<<<<<<<.<......>.>>>>..>>>.<<<.
........>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>....>>..>>>.>>>>>>>......................<<<
<.....>>>>.<<<<<<<<....>>>.>>>>>....<<<<<<<..<....
...>.>>>>>>>..
Receptor-Ligand Complex Structure
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PDB5t2a Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H25 G65 K66 I67 G68 R69 T79 K80 R82 W83 P84 R85 K86 Y130 R131 G134 I136 P138 Y139 M140 C141
Binding residue
(residue number reindexed from 1)		H24 G64 K65 I66 G67 R68 T78 K79 R81 W82 P83 R84 K85 Y129 R130 G133 I135 P137 Y138 M139 C140
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t2a, PDBe:5t2a, PDBj:5t2a
PDBsum5t2a
PubMed27752045
UniProtA0A3S7WY02

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