Structure of PDB 3zha Chain P Binding Site BS02

Receptor Information
>3zha Chain P (length=373) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLGGK
ATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNTWKLGSRLYGPSSVSF
AEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDV
ERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGL
YNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKI
WMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSG
KKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKLFYADHPFIFLV
RDTQSGSLLFIGRLVRPKGDKMR
Ligand information
>3zha Chain S (length=17) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PPGPPGPTGPRGPPGPP
Receptor-Ligand Complex Structure
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PDB3zha Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		R228 L381 Y383
Binding residue
(residue number reindexed from 1)		R186 L339 Y341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005518 collagen binding
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3zha, PDBe:3zha, PDBj:3zha
PDBsum3zha
PubMed22847422
UniProtC7C419

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