Structure of PDB 8vg2 Chain O Binding Site BS02

Receptor Information
>8vg2 Chain O (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNS
IRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK
CE
Ligand information
>8vg2 Chain J (length=196) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcatactaaacgtagacaagttggcctgatgtatatatctgacacgtgc
ctggagactagggagtaatccccttggcggttaaaacgcgggggacagcg
cgtacgtgcgtttaagcggtgctagagctgtctacgaccaattgattccc
tggtatcagcaagtacagtgccctgctgacagagcaggagacacaa
Receptor-Ligand Complex Structure
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PDB8vg2 Cryo-EM structure of FoxA1 and GATA4 in complex with H14 chromatosome
Resolution3.04 Å
Binding residue
(original residue number in PDB)
L193 Y197 R219 H220 S223 W244 L260 R261
Binding residue
(residue number reindexed from 1)
L26 Y30 R52 H53 S56 W77 L93 R94
External links
PDB RCSB:8vg2, PDBe:8vg2, PDBj:8vg2
PDBsum8vg2
PubMed
UniProtP55317|FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha (Gene Name=FOXA1)

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