Structure of PDB 8ro2 Chain O Binding Site BS02

Receptor Information
>8ro2 Chain O (length=288) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMR
FKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNK
EYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHI
CSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLL
KRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV
QRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKW
Ligand information
>8ro2 Chain IN (length=41) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R64 K66 E69 R159 Q196 I198 R201 K212 R216
Binding residue
(residue number reindexed from 1)		R50 K52 E55 R145 Q182 I184 R187 K198 R202
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ9NW64|RBM22_HUMAN Pre-mRNA-splicing factor RBM22 (Gene Name=RBM22)

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