Structure of PDB 8q45 Chain O Binding Site BS02

Receptor Information

>8q45 Chain O (length=320) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LQYGPLAYILGEKATKKMTEKSKLITVDGNICSGKSKLAKEIAEKLGLKH
FPEAGIHYVDSTTGDGKPLPVQFSGNCSLEKFYDDPKSNDGNSYRLQAWL
YASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVD
HYNQVKKVTICEYLPPHVVVYVDVPVPEVQSRIQKKGNPHEMKITSAYLQ
DIENAYKGTFLPEMSEKCEVLQYSAWEAQDAEKVVEDIEYLKYDKGPWLD
QNDRKLHKLRMLVQDKLEVLNYTSIPVFLPEVTVGAHQSDQVFQEFTELP
GRKYRAGYNEDVGDKWIWLK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8q45 Chain O Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8q45 Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I
Resolution	2.7 Å
Binding residue (original residue number in PDB)	K35 S36
Binding residue (residue number reindexed from 1)	K35 S36
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006120	mitochondrial electron transport, NADH to ubiquinone
GO:0032981	mitochondrial respiratory chain complex I assembly

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0045271	respiratory chain complex I

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Biological Process

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Cellular Component

External links

PDB	RCSB:8q45, PDBe:8q45, PDBj:8q45
PDBsum	8q45
PubMed	38870289
UniProt	P34942\|NDUAA_BOVIN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Gene Name=NDUFA10)

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