Structure of PDB 7zhs Chain O Binding Site BS02
Receptor Information
>7zhs Chain O (length=242) Species:
9606,559292
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GEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSAC
RGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIK
EVKILEVHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQR
DGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVV
RGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDL
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
7zhs Chain O Residue 402 [
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Receptor-Ligand Complex Structure
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PDB
7zhs
The class A Hsp40 DnaJA2 self-associates into ordered, highly dynamic tubular oligomers that productively interact with unfolded substrates and Hsc70
Resolution
6.9 Å
Binding residue
(original residue number in PDB)
C89 C92 C116 C119
Binding residue
(residue number reindexed from 1)
C47 C50 C74 C77
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0001671
ATPase activator activity
GO:0005515
protein binding
GO:0005524
ATP binding
GO:0030544
Hsp70 protein binding
GO:0031072
heat shock protein binding
GO:0031386
protein tag activity
GO:0042802
identical protein binding
GO:0044389
ubiquitin-like protein ligase binding
GO:0046872
metal ion binding
GO:0051082
unfolded protein binding
GO:0051087
protein-folding chaperone binding
Biological Process
GO:0006457
protein folding
GO:0008284
positive regulation of cell population proliferation
GO:0009408
response to heat
GO:0016925
protein sumoylation
GO:0042026
protein refolding
Cellular Component
GO:0000794
condensed nuclear chromosome
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005940
septin ring
GO:0016020
membrane
GO:0070062
extracellular exosome
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7zhs
,
PDBe:7zhs
,
PDBj:7zhs
PDBsum
7zhs
PubMed
37670029
UniProt
O60884
;
Q12306
|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3)
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