Structure of PDB 7m4y Chain O Binding Site BS02

Receptor Information
>7m4y Chain O (length=116) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKHPLVQAIENSQLKTDLPEFAPGDTVVVQVKVKEGDRERLQAFEGVVIA
KKNRGLNSAFTVRKISSGVGVERVFQTHSPVVAKIEVKRRGDVRRAKLYY
LRDLSGKAARIREKLP
Ligand information
>7m4y Chain a (length=1528) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaacugaagaguuugaucauggcucagauugaacgcuggcggcaggcuua
acacaugcaagucgagcgggggaagguagcuugcuaccggaccuagcggc
ggacgggugaguaaugcuuaggaaucugccuauuagugggggacaacauc
ucgaaagggaugcuaauaccgcauacguccuacgggagaaagcaggggau
cuucggaccuugcgcuaauagaugagccuaagucggauuagcuaguuggu
gggguaaaggccuaccaaggcgacgaucuguagcgggucugagaggauga
uccgccacacugggacugagacacggcccagacuccuacgggaggcagca
guggggaauauuggacaauggggggaacccugauccagccaugccgcgug
ugugaagaaggccuuaugguuguaaagcacuuuaagcgaggaggaggcua
cucuaguuaauaccuagggauaguggacguuacucgcagaauaagcaccg
gcuaacucugugccagcagccgcgguaauacagagggugcgagcguuaau
cggauuuacugggcguaaagcgugcguaggcggcuuauuaagucggaugu
gaaauccccgagcuuaacuugggaauugcauucgauacuggugagcuaga
guaugggagaggaugguagaauuccagguguagcggugaaaugcguagag
aucuggaggaauaccgauggcgaaggcagccaucuggccuaauacugacg
cugagguacgaaagcauggggagcaaacaggauuagauacccugguaguc
caugccguaaacgaugucuacuagccguuggggccuuugaggcuuuagug
gcgcagcuaacgcgauaaguagaccgccuggggaguacggucgcaagacu
aaaacucaaaugaauugacgggggcccgcacaagcgguggagcauguggu
uuaauucgaugcaacgcgaagaaccuuaccuggccuugacauacuagaaa
cuuuucagagauggauuggugccuucgggaaccuagauacaggugcugca
uggcugucgucagcucgugucgugagauguuggguuaagucccgcaacga
gcgcaacccuuuuccuuacuugccagcauuucggaugggaacuuuaagga
uacugccagugacaaacuggaggaaggcggggacgacgucaagucaucau
ggcccuuacggccagggcuacacacgugcuacaauggucgguacaaaggg
uugcuacacagcgaugugaugcuaaucucaaaaagccgaucguaguccgg
auuggagucugcaacucgacuccaugaagucggaaucgcuaguaaucgcg
gaucagaaugccgcggugaauacguucccgggccuuguacacaccgcccg
ucacaccaugggaguuuguugcaccagaaguagcuagccuaacugcaaag
agggcgguuaccacgguguggccgaugacuggggugaagucguaacaagg
uagccguaggggaaccugcggcuggauc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<<...<<<<<....>>>>>...>>>.>>>>>
......<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<
<......>>>>>......>>.>.....<<<....>>>....<<<<<<..<
<....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>
>>>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<
<<<......<<<<....>>>>.....>>>>...<.<<<<<......<<<<
<<<<<<.......>>>>>>.>>>>........>>>>>....>..<<<<<(
((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>
>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<
......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>...<
<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>......
>>>>>>>>...........<<....>>.>>>>>>>..>>>.>>>>>...>
>>...>>>>....<<<<<<...<<...<<<<.........>>>>...>>>
>>>>>..........<<<<<<..<<<<<<<<<<<<<...>>>>>>>>>>>
>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<
......<<........>>..........<<<<<<<......<<<<<<...
<..<<<<....>>>>..>...<<....>>...>>>>.>>.<<<.<<<..<
<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>
>>.....<<<<.<<<<<<....<<..<<<.....>>>>>.....>>>>>>
.....<<<<<.....>>>>>........>>>>.........>>>...>>>
>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<
..<<..<<<<....>>>>..>>....>>>.....>>>>>>>......<..
..<<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<
<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..<<
.<.<<<<.<<<..<<<.<<<<<<<<....<<<<<<.<<<<..<<....>>
.>>>>>>>>>>...>>>>>>>>.>>>..>>>.>>>>..>.>>...>....
.<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB7m4y Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R40 R42 R112
Binding residue
(residue number reindexed from 1)		R38 R40 R110
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7m4y, PDBe:7m4y, PDBj:7m4y
PDBsum7m4y
PubMed34044590
UniProtB7IAS9|RL19_ACIB5 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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