Structure of PDB 7et3 Chain O Binding Site BS02

Receptor Information
>7et3 Chain O (length=69) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVTMDRVRKRYLR
QELRDLGHRVQTYCEDLEG
Ligand information
>7et3 Chain P (length=20) Species: 10359 (Human betaherpesvirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LRQLAQSVQDTIQHMRFLYL
Receptor-Ligand Complex Structure
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PDB7et3 Structural basis for genome packaging, retention, and ejection in human cytomegalovirus.
Resolution4.2 Å
Binding residue
(original residue number in PDB)
L61 E64 L65 L68 R71 Y75
Binding residue
(residue number reindexed from 1)
L49 E52 L53 L56 R59 Y63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019072 viral genome packaging
GO:0019073 viral DNA genome packaging
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019028 viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7et3, PDBe:7et3, PDBj:7et3
PDBsum7et3
PubMed34315863
UniProtP16726|CVC2_HCMVA Capsid vertex component 2 (Gene Name=CVC2)

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