Structure of PDB 6iy3 Chain O Binding Site BS02

Receptor Information
>6iy3 Chain O (length=580) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQ
IKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLV
IVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLT
TFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLI
LTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETL
LVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQML
KYRRLGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFEL
LDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDE
RSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDL
QAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKF
DNKSTSEEQEALLRSLLDAEEERRKKRELKDSEINEILARNDEEMAVLTR
MDEDRSKKEEKSRLLEKKREESESAAVYNG
Ligand information
>6iy3 Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaaaactgtgccgcagtcggccgacctgagggtcgccggggtctgcgg
ggggaccctctggaaagtgaaggataagtgacgagcggagacgggatggc
gaacagacacaaacacacaagaggtgaatgttaggactgttgcagat
Receptor-Ligand Complex Structure
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PDB6iy3 Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Resolution3.67 Å
Binding residue
(original residue number in PDB)		L825 E874 Y875 K878 N1050 M1053 K1057 M1112 T1113 Q1114 G1135 R1142 S1162 G1166
Binding residue
(residue number reindexed from 1)		L104 E153 Y154 K157 N309 M312 K316 M371 T372 Q373 G394 R401 S421 G425
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity

View graph for
Molecular Function
External links
PDB RCSB:6iy3, PDBe:6iy3, PDBj:6iy3
PDBsum6iy3
PubMed30867599
UniProtP22082|SNF2_YEAST Transcription regulatory protein SNF2 (Gene Name=SNF2)

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