Structure of PDB 5x0x Chain O Binding Site BS02

Receptor Information
>5x0x Chain O (length=583) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLDQTKDTRITHLLRQTNAFLDYYNVAHRIKEDIKKQPSILVGGTLKDYQ
IKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLV
IVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLT
TFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLI
LTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFDKIELSEEETL
LVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQML
KYRRLRGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFE
LLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSD
ERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQD
LQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGK
FDNKSTSEEQEALLRSLLDAEEERRKKREELKDSEINEILARNDEEMAVL
TRMDEDRSKKEEKSRLLEKKREESESAAVYNGR
Ligand information
>5x0x Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcga
Receptor-Ligand Complex Structure
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PDB5x0x Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Resolution3.97 Å
Binding residue
(original residue number in PDB)
L825 E874 Y875 K878 M1112 T1113 Q1114 G1135 R1142 A1165
Binding residue
(residue number reindexed from 1)
L104 E153 Y154 K157 M372 T373 Q374 G395 R402 A425
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity

View graph for
Molecular Function
External links
PDB RCSB:5x0x, PDBe:5x0x, PDBj:5x0x
PDBsum5x0x
PubMed28424519
UniProtP22082|SNF2_YEAST Transcription regulatory protein SNF2 (Gene Name=SNF2)

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