Structure of PDB 4l3c Chain O Binding Site BS02

Receptor Information
>4l3c Chain O (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4l3c Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
Resolution2.64 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 T73 H74 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 T73 H74 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4l3c, PDBe:4l3c, PDBj:4l3c
PDBsum4l3c
PubMed24338476
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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