Structure of PDB 3mva Chain O Binding Site BS02

Receptor Information
>3mva Chain O (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIA
SIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNN
NLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAG
LSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLV
LICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIF
LAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCN
LSTLNITLLSWSKKRYEAKLKKLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mva Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		G95 H98 R99 R130 R134 R169 S170 R202 S207 L210 S248 R251 S285 Y288 L323 A324 K327 K331 D353 S354 S355 T358 S384 K385 R387
Binding residue
(residue number reindexed from 1)		G23 H26 R27 R58 R62 R97 S98 R130 S135 L138 S176 R179 S213 Y216 L251 A252 K255 K259 D281 S282 S283 T286 S312 K313 R315
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003690 double-stranded DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3mva, PDBe:3mva, PDBj:3mva
PDBsum3mva
PubMed20550934
UniProtQ99551|MTEF1_HUMAN Transcription termination factor 1, mitochondrial (Gene Name=MTERF1)

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