Structure of PDB 3h1c Chain O Binding Site BS02

Receptor Information
>3h1c Chain O (length=544) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKA
KPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIR
PLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIG
AARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQ
MLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALA
EARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAI
EKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQA
LVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRRE
IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRD
GISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAP
Ligand information
>3h1c Chain P (length=21) Species: 83333 (Escherichia coli K-12) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAAGGHTATHHASAAPARPQP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3h1c Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly
Resolution3.57 Å
Binding residue
(original residue number in PDB)		D322 M323 I324 G326 L327 D328 V329 R330 T331 G332 V333 P335 G528 A540 I541
Binding residue
(residue number reindexed from 1)		D322 M323 I324 G326 L327 D328 V329 R330 T331 G332 V333 P335 G528 A540 I541
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3h1c, PDBe:3h1c, PDBj:3h1c
PDBsum3h1c
PubMed19327365
UniProtP05055|PNP_ECOLI Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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