Structure of PDB 2clb Chain O Binding Site BS02

Receptor Information
>2clb Chain O (length=169) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QEPKVVGVEILEKSGLDIKKLVDKLVKATAAEFTTYYYYTILRMHLTGME
GEGLKEIAEDARLEDRLHFELMTQRIYELGGGLPRDIRQLADISACSDAY
LPENWKDPKEILKVLLEAEQCAIRTWKEVCDMTYGKDPRTYDLAQRILQE
EIEHEAWFLELLYGRPSGH
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain2clb Chain O Residue 1176 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2clb Structure of the Dps-Like Protein from Sulfolobus Solfataricus Reveals a Bacterioferritin-Like Dimetal Binding Site within a Dps-Like Dodecameric Assembly.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D70 E124 E156 H159
Binding residue
(residue number reindexed from 1)		D65 E119 E151 H154
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.-.-
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009295 nucleoid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2clb, PDBe:2clb, PDBj:2clb
PDBsum2clb
PubMed16953567
UniProtP95855|DPS_SACS2 DNA protection during starvation protein (Gene Name=dps)

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