Structure of PDB 8fla Chain NR Binding Site BS02

Receptor Information
>8fla Chain NR (length=152) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDP
QKKRYSKKDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIK
QTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICAN
DA
Ligand information
>8fla Chain L4 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB8fla Principles of human pre-60 S biogenesis.
Resolution2.63 Å
Binding residue
(original residue number in PDB)		R29 K36 K151 P154 N155
Binding residue
(residue number reindexed from 1)		R15 K22 K137 P140 N141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:1990275 preribosome binding
Biological Process
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fla, PDBe:8fla, PDBj:8fla
PDBsum8fla
PubMed37410842
UniProtQ96EY4|TMA16_HUMAN Translation machinery-associated protein 16 (Gene Name=TMA16)

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