Structure of PDB 8fkv Chain NM Binding Site BS02

Receptor Information
>8fkv Chain NM (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQ
YATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIY
WPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREE
KALIAAQLDNAIEKELLERLKQDTYGDIYNFP
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8fkv Chain NM Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fkv Principles of human pre-60 S biogenesis.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		C17 F19 K20 C29 C39 C44 L46
Binding residue
(residue number reindexed from 1)		C17 F19 K20 C29 C39 C44 L46
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000460 maturation of 5.8S rRNA
GO:0000470 maturation of LSU-rRNA
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fkv, PDBe:8fkv, PDBj:8fkv
PDBsum8fkv
PubMed37410842
UniProtQ9BXY0|MAK16_HUMAN Protein MAK16 homolog (Gene Name=MAK16)

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