Structure of PDB 8wi7 Chain N Binding Site BS02

Receptor Information
>8wi7 Chain N (length=122) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGG
NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIKNDNDPRGTRIFG
PVGRELREKKFMKIVSLAPEVL
Ligand information
>8wi7 Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac
augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg
gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa
acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg
aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg
ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc
ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu
ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag
ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa
gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc
gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc
ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg
gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu
ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga
aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag
cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua
gguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagua
ccccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgg
gggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaag
aaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguuc
ccuuguggccugugugcagguggugcauggcugucgucagcucgugucgu
gagauguuggguuaagucccgcaacgagcgcaacccuugucucauguugc
cagcacguuaugguggggacucgugagagacugccggggucaacucggag
gaagguggggaugacgucaagucaucaugccccuuauguccagggcuuca
cacaugcuacaauggccgguacaaagggcugcgaugccgugagguggagc
gaauccuuucaaagccggucucaguucggaucggggucugcaacucgacc
ccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaa
uacguucccgggccuuguacacaccgcccgucacgucaugaaagucggua
acacccgaagccgguggccuaacccuuguggagggagccgucgaaggugg
gaucggcgauugggacgaagucguaacaagguagccguaccggaaggugc
ggcuggaucaccucc
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>......
<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<...
.>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>.
...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<
<......<<<<....>>>>.....>>>>...<.<<<<<......<<....
>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>>
.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<
<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>>
>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<<
<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<..
..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<
<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<..
<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>>
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.
<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>...
.......<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.<
<.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<..
..>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<
<..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>..
......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.
>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>
....>>>......>>>>>>>......<....<<<<<<<........>>>>
>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<.
.<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>.
.>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>
>>>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wi7 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
P48 R97
Binding residue
(residue number reindexed from 1)
P48 R97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8wi7, PDBe:8wi7, PDBj:8wi7
PDBsum8wi7
PubMed38245551
UniProtA0QSF9|RL14_MYCS2 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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