Structure of PDB 8ow1 Chain N Binding Site BS02

Receptor Information
>8ow1 Chain N (length=386) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NELRLEDNYVPTSDTLVVFKQLMKLPVTVLYDLTLSWFAKFGGSFDGDIY
LLTETLDLLIEKGVRRNVIVNRILYVYWPDGLNVFQLAEIDCHLMISKPE
KFKWLPSKALRGDGKPYVVKLQPAKFIENLQTDLAKIYHCHVYMFKHPSL
PVLITRIQLFDSNKPLISRRPYYVAFPLNSPIIFHSVDKDIYARLVLQSI
SRTISERETIIFKPVQKIPVKSIHNIMTLLGPSRFAESMGPWECYASANF
ERSPLHDYKKHQGLTGKKVMVREFDDSFLNDGKEEPEIRRLRLEKNMIKF
KGSANGVMSRYSSLVPIEKVGFTLKNEINSRIITIKLKFNGNDIFGGLHE
LCDKNLINIDKVPGWLAGENGSFSGTIMNGDFQREQ
Ligand information
>8ow1 Chain E (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttcaatgaaatatatatttcttactatttcttttttaactttcggaaatc
aaatacactaatattaaaacgcgggggacagcgcgtacgtgcgtttaagc
ggtgctagagctgtctacgaccaattgagcggcctcggcaccatgtgact
tat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ow1 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		M25 K26 L27 R67 R68 N69
Binding residue
(residue number reindexed from 1)		M23 K24 L25 R65 R66 N67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0034080 CENP-A containing chromatin assembly
GO:0034087 establishment of mitotic sister chromatid cohesion
GO:0034089 establishment of meiotic sister chromatid cohesion
GO:0034090 maintenance of meiotic sister chromatid cohesion
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051382 kinetochore assembly
GO:0071459 protein localization to chromosome, centromeric region
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000940 outer kinetochore
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ow1, PDBe:8ow1, PDBj:8ow1
PDBsum8ow1
PubMed37506202
UniProtP38907|CENPN_YEAST Inner kinetochore subunit CHL4 (Gene Name=CHL4)

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