Structure of PDB 7uvx Chain N Binding Site BS02
Receptor Information
>7uvx Chain N (length=115) Species:
480119
(Acinetobacter baumannii AB0057) [
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NEKKQSRLRRAKSTRLHIRALGATRLCVNRTPRHIYAQVISADGGKVLAQ
ASTLDASLRSGTTGNIEAATKVGALIAERAKAAGVTKVAFDRSGFKYHGR
IKALADAAREGGLEF
Ligand information
>7uvx Chain B (length=115) [
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gcuggcgaccauagcaagagugaaccaccugaucccuucccgaacucaga
agugaaaccucuuagcgcugaugguagugugggauuacccaugugagagu
aagucaucgccagcu
<<<<<<<<.....<<<<<<<.....<<<<<<...............>>>.
.>>>....>>>>>.>><<<.......<<<<<<<....>>>>>>>......
.>>>..>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
7uvx
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
K4 K5 R16 R20 R26 R31 T32 R34 H35 Y37 Q39 G45 G46 V48 Q51 R60 N66 I67 H99 R101
Binding residue
(residue number reindexed from 1)
K3 K4 R15 R19 R25 R30 T31 R33 H34 Y36 Q38 G44 G45 V47 Q50 R59 N65 I66 H98 R100
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:7uvx
,
PDBe:7uvx
,
PDBj:7uvx
PDBsum
7uvx
PubMed
37192172
UniProt
B7IA23
|RL18_ACIB5 Large ribosomal subunit protein uL18 (Gene Name=rplR)
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