Structure of PDB 7oid Chain N Binding Site BS02

Receptor Information
>7oid Chain N (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGY
LHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGA
IDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLE
KMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFY
MPKRV
Ligand information
>7oid Chain A (length=1472) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagcaaccuuagcc
aaaccauuuacaaauaaaguauaggcgauagaaauugauggcgcaauaga
uauaguaccgcaagggaaagaugaaaaauuauaaccaagcauaauauagc
aaggacuaaccccuauaccuucugcauaaugaauuaacuagaaauaacuu
ugcaaggagagccaaagcuaagacccccgaaaccagacgagcuaccuaag
aacagcuaagagcacacccgucuauguagcaaaauagugggaagauuuau
agguagaggcgacaaaccuaccgagccuggugauagcugguuguccaaga
uagaaucuuaguucaacuuuaaauuugcccacagaaccaaauccccuugu
aaauuuaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaa
aaccuuguagagagaguaaaaaauuuaacacccauaguaggccuaaaagc
agccaccaauuaagaaagcguucaagcucaacaccaaaaaucccaaacau
auaacugaacuccucacacccaauuggaccaaucuaucacccuauagaag
aacuaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccu
gcgucagauacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacacaggcaugcucauaaggaaag
guuaaaaaaaguaaaaggaacucggcaaaucuuaccccgccuguuuacca
aaaacaucaccucuagcaucaccaguauuagaggcaccgccugcccagug
acacauguuuaacggccgcgguuaaccgugcaaagguagcauaaucacuu
guuccuuaaauagggaccuguaugaauggcuccacgaggguucagcuguc
ucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggcauaa
cacagcaagacgagaagacccuauggagcuuuaauuuauuaaugcaaaca
guaaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauu
gauccaauaacuugaccaacggaacaaguuacccuagggauaacagcgca
auccuauucuagaguccauaucaacaauaggguuuacgaccucgauguug
gaucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaa
cgauuaaaguccuacgugaucugaguucagaccggaguaauccaggucgg
uuucuaucuacuuuauuccucccuguacgaaaggacaagagaaauaaggc
cuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagau
acccacacccaagaacaggguu
<<<.......<<<<....................................
<......>.......<.....<<.....>>....>....>>.>>......
.......<<....>>......................>>>..........
.<<<.......>>>...<.<........>.>.<<<<<<.........<<<
.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<
<<..<<<...>>>...<<<<.<<<<........>>>>>>>>....>>>.>
>>>>...<<.......>>......>.>>>>......>.>>..<<<<<<..
..<<<<....>>>><<<.<<<<<<<<<<.....<<......>>.....>>
>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>...<<<....
..>>>....<<<.<<<...<..............<....<<<........
.>>>....>.......<<<......>>>......................
.....>...>>>>>>........>>>>>>...<<<<<......>>>>>..
.......>>>>>>.......<<..<<<....>>><<<<..<<<<......
..<<<<<...>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<......>>.>>>>.....>>>>..<
<<<...<<<<<<<<.<<.........<......<<<<<<..<<<......
...>>>...<<<<<<.............>>>>>>....<<<.<<<..<<<
<<....>>>..>>>>><<<<<....>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>....>>.>>>>.....>..>
>.>>>>>>>>>>>>.>>...........<<<<<........>>>>>....
...<<..<<<.<<......<<<<.<<<<<<..<<<<..<<<<<<<<....
......>>>>>>>>.>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
....<<<....>>>............>>>>..>>>>>>.......<<<..
<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.......<<<
<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>
>>>.....>>>>>..>...>>>>.>....<<<<<<<....>>>.>>>>..
..>>..>>>.>>..<<<.<<<.................>>>.>>><<<<<
...<<<....>>>.>>>>>......<<<................>>>...
......<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7oid A distinct assembly pathway of the human 39S late pre-mitoribosome.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R63 R64 P66 K67 Y96 H101 E103 R111 R133 K134 R139 M140 G141 G142 G143 K144 Q178 K182 V229 L230 S231 P232
Binding residue
(residue number reindexed from 1)		R17 R18 P20 K21 Y50 H55 E57 R65 R87 K88 R93 M94 G95 G96 G97 K98 Q132 K136 V183 L184 S185 P186
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7oid, PDBe:7oid, PDBj:7oid
PDBsum7oid
PubMed34315873
UniProtQ9NX20|RM16_HUMAN Large ribosomal subunit protein uL16m (Gene Name=MRPL16)

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