Structure of PDB 6mup Chain N Binding Site BS02

Receptor Information
>6mup Chain N (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGFDMKQFKNS
FKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQ
TPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFK
QYNQT
Ligand information
>6mup Chain J (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgaggaagttcatataaaaggcaaacggaagcattctcagaatattct
ttgtgatgatggagtttcactcacagagctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatatttgat
Receptor-Ligand Complex Structure
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PDB6mup Structure of the Human Core Centromeric Nucleosome Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
P17 M18 R44 K45 R169
Binding residue
(residue number reindexed from 1)
P17 M18 R44 K45 R162
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly

View graph for
Biological Process
External links
PDB RCSB:6mup, PDBe:6mup, PDBj:6mup
PDBsum6mup
PubMed31353180
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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