Structure of PDB 6hkt Chain N Binding Site BS02

Receptor Information
>6hkt Chain N (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR
LAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>6hkt Chain J (length=1122) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgctgttcaatacatgcacaggatgtatatatctgacacgtgcctgga
gactagggagtaatccccttggcggttaaaacgcgggggacagcgcgtac
gtgcgtttaagcggtgctagagctgtctacgaccaattgagcggcctcgg
caccgggattctccagggcggccgcgtatagggtctcggggctgttcaat
acatgcacaggatgtatatatctgacacgtgcctggagactagggagtaa
tccccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcg
gtgctagagctgtctacgaccaattgagcggcctcggcaccgggattctc
cagggcggccgcgtatagggtctcggggctgttcaatacatgcacaggat
gtatatatctgacacgtgcctggagactagggagtaatccccttggcggt
taaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagctgt
ctacgaccaattgagcggcctcggcaccgggattctccagggcggccgcg
tatagggtctcggggctgttcaatacatgcacaggatgtatatatctgac
acgtgcctggagactagggagtaatccccttggcggttaaaacgcggggg
acagcgcgtacgtgcgtttaagcggtgctagagctgtctacgaccaattg
agcggcctcggcaccgggattctccagggcggccgcgtatagggtctcgg
ggctgttcaatacatgcacaggatgtatatatctgacacgtgcctggaga
ctagggagtaatccccttggcggttaaaacgcgggggacagcgcgtacgt
gcgtttaagcggtgctagagctgtctacgaccaattgagcggcctcggca
ccgggattctccagggcggccgcgtatagggtctcggggctgttcaatac
atgcacaggatgtatatatctgacacgtgcctggagactagggagtaatc
cccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggt
gctagagctgtctacgaccaattgagcggcctcggcaccgggattctcca
gggcggccgcgtatagggtgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6hkt Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
Resolution9.7 Å
Binding residue
(original residue number in PDB)		R28 S29 R30 K31 S33 Y37
Binding residue
(residue number reindexed from 1)		R2 S3 R4 K5 S7 Y11
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001530 lipopolysaccharide binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0002227 innate immune response in mucosa
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0019731 antibacterial humoral response
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0061644 protein localization to CENP-A containing chromatin
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0000786 nucleosome
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0043505 CENP-A containing nucleosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hkt, PDBe:6hkt, PDBj:6hkt
PDBsum6hkt
PubMed30392928
UniProtP06899|H2B1J_HUMAN Histone H2B type 1-J (Gene Name=H2BC11)

[Back to BioLiP]