Structure of PDB 3qrf Chain N Binding Site BS02

Receptor Information
>3qrf Chain N (length=286) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSVPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPV
VQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKI
VGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRV
RLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYG
GQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVAAAAAAPNMLFVEI
PEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3qrf Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y424 T426 K520 R522 N523 R537 K538 R572 R665
Binding residue
(residue number reindexed from 1)		Y32 T34 K128 R130 N131 R145 K146 R180 R273
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3qrf, PDBe:3qrf, PDBj:3qrf
PDBsum3qrf
PubMed21458306
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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