Structure of PDB 3q7h Chain N Binding Site BS02

Receptor Information
>3q7h Chain N (length=192) Species: 360115 (Coxiella burnetii RSA 331) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLVPMVVEQTSRGERAYDIYSRLLKDRVIFLVGQVEDHMANLAIAQMLFL
ESENPNKDINLYINSPGGAVTSAMAIYDTMQFVKPDVRTLCIGQAASAGA
LLLAGGAKGKRHCLPHSSVMIHQVLGGYQGQGTDIQIHAKQTQRVSDQLN
QILAKHTGKDIERVEKDTNRDYFLTPEEAVEYGLIDSIFKER
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3q7h Chain N Residue 199 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3q7h Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii
Resolution2.5 Å
Binding residue
(original residue number in PDB)		A71 V72 V126 L127
Binding residue
(residue number reindexed from 1)		A69 V70 V124 L125
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) G70 S99 A100 H124 D173
Catalytic site (residue number reindexed from 1) G68 S97 A98 H122 D171
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0051117 ATPase binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Cellular Component
GO:0005737 cytoplasm
GO:0009368 endopeptidase Clp complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3q7h, PDBe:3q7h, PDBj:3q7h
PDBsum3q7h
PubMed
UniProtQ83DJ2|CLPP_COXBU ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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