Structure of PDB 3jcs Chain N Binding Site BS02

Receptor Information
>3jcs Chain N (length=213) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MARRPSRCYRFCKNKPYPKSRFCRGVPDPKIRNFDIGRRRATVDEFPVCI
HVVSRELEQIASEALEAARIQANKYMVKRANKDVFHMRTRAHPFHVLRIN
KMLSCAGADRLQTGMRGAFGKPNGVCARVRIGQILLSMRTKEAYVPQAFE
ALRRAKMKFPGRQIIVMSKYWGFTNILRTEYEALRDAGKLEQRGTHCKLI
APKGKITMRNVMA
Ligand information
>3jcs Chain 2 (length=1119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccacucagaacu
gcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaugc
auccaagugguguauaucgcaaacugauuucugcccagugcucugaaugu
caacgugacgagauucaccgacgcgcggguaaacggcgggagacucucuu
aagguagccaaaugccucgucuuccaauuagagacgcgcaugaauggauu
aaugagauucccucugucccgaguuacuaucuagcgaaacgacagucaag
ggaacggacuugaagggcuaagcggggaaagaagacccuguugaguuuga
cuccagucuggcucugugcggcgacaucugagguguaguauagguggaag
cgcaagcgcaaaugaaauaccaccacucggaaguugcuucacuuaucgaa
ugaagagaccaauggguuuagcguagucuggcuaugcaccgucuagguuu
gggaguaauuuuauggcggggugugcuugggcgugacucguggguaccca
accgugcuguaaacugaaccaacgggauugccucgugcaguuccgggucu
uguuucgagacaucugccagauggggaguuuggcugcggcuaucuguuac
acgacaacgcagguguccuaaggcgagcucagugggaacaaucucacgua
gaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaaucga
gacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauaccag
aggugucagaauaauuaccacagggauaacuggcuuguggcggccaagcg
auagcgacgucgcuuuuugauccuucgaugucggcucuuccuaaccuagc
gccgcagaagacgcuaaggguuggauuguucacccacugacagggaacgu
gagcuggguuuagaccgucgugagacagguugguuuuacccuacuuagcu
ggaaauugcgagaaaaaga
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<...............<<<<
<.....<..>......>>>>><<.<<<<<<.<......>..>>>>>>.>>
..........<<<<<<<<<..<<<.........>>>..<<<<<<<....<
<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<<
....<<<<......>>>>....>>..>>>>..>>>>>.............
......<...........<<<<<.......>>>>>.....>.....>>..
..>>.>>>>>>>.....>>.>>>>>>>>.>>>>............<<<<<
........>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<
<<<<.<<<<<<<...<<<.<<<<<<.<<<.....................
............................>>>.>>>>>>.>>>...<<<<<
.....<<<.....<<.....<<<<<<<...>>>>>>>....>>.....<.
..<..................<<<<<<..>>>>>>...............
..>..>................<<<<<<<<.......>>>>>>>>..>>>
...>>>>>.......>>>>>>>..>>>>>..<<<....>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<....>>>>>>...
..<<......>>....>>>>>>>...<<..<<<<<<.......>>>>>>.
>>.<<<....>>>.>>........<<<<<<..<<<.......>>>..>>>
>>>.........>>>>..>>>>>>.......<<.<...<.<.<.....<.
...>.....>.>.>....>.>.>.......<<<<<.<<<<<<..<<<<<<
<.<......>.>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>>>>>
...................
Receptor-Ligand Complex Structure
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PDB3jcs 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
M1 A2 R3 R4 P5 R7 K15 F22 E63 K74 Y75 K78 L103 T113 R116 F119 R154 M157 K158 P160
Binding residue
(residue number reindexed from 1)
M1 A2 R3 R4 P5 R7 K15 F22 E63 K74 Y75 K78 L103 T113 R116 F119 R154 M157 K158 P160
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3jcs, PDBe:3jcs, PDBj:3jcs
PDBsum3jcs
PubMed27373148
UniProtA0A3S5H5C4

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