Structure of PDB 1a02 Chain N Binding Site BS02

Receptor Information
>1a02 Chain N (length=280) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGY
MENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKV
LEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRV
HIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMIL
TGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNK
HIRTPVKVNFYVINGKRKRSQPQHFTYHPV
Ligand information
Receptor-Ligand Complex Structure
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PDB1a02 Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y424 T426 R522 N523 R537 K538 R572 R665
Binding residue
(residue number reindexed from 1)		Y26 T28 R124 N125 R139 K140 R174 R267
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1a02, PDBe:1a02, PDBj:1a02
PDBsum1a02
PubMed9510247
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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