Structure of PDB 8bhf Chain M3 Binding Site BS02

Receptor Information

>8bhf Chain M3 (length=143) Species: 9986 (Oryctolagus cuniculus)

DIQTERAYQKQPTIFQNKKRVKLPRYYKNIGLGFKTPKEAIEGTYIDKKC
PFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMS
VHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8bhf Chain M3 Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8bhf Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): R97 K98 N100
• Binding residue (residue number reindexed from 1): R87 K88 N90
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8bhf, PDBe:8bhf, PDBj:8bhf
• PDBsum: 8bhf
• PubMed: 37653241
• UniProt: G1TRM4|RS11_RABIT Small ribosomal subunit protein uS17 (Gene Name=RPS11)