Structure of PDB 7r81 Chain M1 Binding Site BS02

Receptor Information

>7r81 Chain M1 (length=165) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PMRELRIQKLVLNICVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTF
GIRRNEKISVHVTVRGPKAEEILERGLKVKEYELRKRNFSETGNFGFGIS
EHIDLGIKYDPGIGIYGMDFYCCMTRPGERVSRRRRAKSRVGATHRITRD
DTVKWFKSRFDAIVR

Ligand information

>7r81 Chain B1 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acauacgaccauacccacuggaaaacucgggaucccguccgcucucccau
agauaagccagugagggccagacuaguaguugggucggugacgaccagcg
aaucccugguguuguauguu

<<<<<<<<<....<<<<<<<<.....<<<<<<............>>>>..
.>>....>>>>>>.>><<<<<.......<<<<<..<<....>>.>>>>>.
.....>>>>>>>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7r81 Structure of the translating Neurospora ribosome arrested by cycloheximide
Resolution	2.7 Å
Binding residue (original residue number in PDB)	M11 Q45 T46 V48 T72 R74 R139 V140 R143 R145 S148 R149 G151 A152 H154
Binding residue (residue number reindexed from 1)	M2 Q36 T37 V39 T63 R65 R130 V131 R134 R136 S139 R140 G142 A143 H145

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:7r81, PDBe:7r81, PDBj:7r81
PDBsum	7r81
PubMed	34815343
UniProt	Q7RVN0\|RL11_NEUCR Large ribosomal subunit protein uL5 (Gene Name=rpl-11)

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