Structure of PDB 8y39 Chain M Binding Site BS02

Receptor Information
>8y39 Chain M (length=119) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKG
VTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYL
YHGRVKALAEAARESGLEF
Ligand information
>8y39 Chain B (length=115) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucuggugacuauagcaaggaggucacaccuguucccaugccgaacacaga
aguuaagcuccuuagcgucgaugguagucgaacuuacguuccgcuagagu
agaacguugccaggc
<<<<<<<<<....<<<<<<<<.....<<<<<...............>>>.
.>>....>>>>>>.>>.<<......<<<.<<<<....>>>>.>>>.....
.>>..>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB8y39 Synthetic macrolides overcoming MLS B K-resistant pathogens.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D6 K7 R11 R30 N32 Y34 R35 S36 N37 K38 H39 Q43 T52 Q55 T68 V70 L100 H102 G103 R104
Binding residue
(residue number reindexed from 1)		D6 K7 R11 R30 N32 Y34 R35 S36 N37 K38 H39 Q43 T52 Q55 T68 V70 L100 H102 G103 R104
Gene Ontology
Molecular Function
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8y39, PDBe:8y39, PDBj:8y39
PDBsum8y39
PubMed38992047
UniProtQ7A085|RL18_STAAW Large ribosomal subunit protein uL18 (Gene Name=rplR)

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