Structure of PDB 8ree Chain M Binding Site BS02

Receptor Information
>8ree Chain M (length=329) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGTPSGNGVGETTQSLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYL
TIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLS
QFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQ
SLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSDSLPSANDTLLRV
SRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSP
RGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLT
SMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8ree Chain T (length=49) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atgaatgtgcaacagcatgatcgcggcaacgtgcaaaagtcgtgccagc
Receptor-Ligand Complex Structure
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PDB8ree Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		M376 H377 H406 V407 A454 R456 T457
Binding residue
(residue number reindexed from 1)		M233 H234 H263 V264 A311 R313 T314
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8ree, PDBe:8ree, PDBj:8ree
PDBsum8ree
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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