Structure of PDB 8qsj Chain M Binding Site BS02

Receptor Information
>8qsj Chain M (length=291) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QGGGARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKG
ERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLI
DLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIE
VQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRML
PPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKM
LCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8qsj Chain M Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qsj Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R43 R44 R47
Binding residue
(residue number reindexed from 1)		R38 R39 R42
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:1990830 cellular response to leukemia inhibitory factor
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qsj, PDBe:8qsj, PDBj:8qsj
PDBsum8qsj
PubMed38042949
UniProtQ9P015|RM15_HUMAN Large ribosomal subunit protein uL15m (Gene Name=MRPL15)

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