Structure of PDB 7qxi Chain M Binding Site BS02

Receptor Information
>7qxi Chain M (length=403) Species: 573 (Klebsiella pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTPQLQQAIRLLQLSTLELQQELQQALESNPLLEEPVYQGETTQTLQDYL
MWQVELTPFTDTDRAIATSIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEE
VEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFAKETPWLEEARLIISDHL
DLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDPRPGQSIQTSEPEYVIP
DVLVRKVSGRWTVELNADSIPRLKINQQYAAMGNSARNDADGQFIRSNLQ
EARWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAV
EMHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRALV
KKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQRK
QLV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qxi Mechanisms of DNA opening revealed in AAA+ transcription complex structures.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
L19 I23 S335 H377 S379 T380 S405 H406 V407 N408 S417 R456 T457 K460
Binding residue
(residue number reindexed from 1)
L5 I9 S261 H303 S305 T306 S331 H332 V333 N334 S343 R382 T383 K386
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0016491 oxidoreductase activity
GO:0016779 nucleotidyltransferase activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7qxi, PDBe:7qxi, PDBj:7qxi
PDBsum7qxi
PubMed36542713
UniProtA0A0H3H3L1

[Back to BioLiP]