Structure of PDB 7qwp Chain M Binding Site BS02

Receptor Information
>7qwp Chain M (length=405) Species: 573 (Klebsiella pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTPQLQQAIRLLQLSTLELQQELQQALESNPLLEEELPVYQGETTQTLQD
YLMWQVELTPFTDTDRAIATSIVDAVDDTGYLTIQIEDIVDSIGDDEIGL
EEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFAKETPWLEEARLIISD
HLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDPRPGQSIQTSEPEYV
IPDVLVRKVSGRWTVELNADSIPRLKINQQYAAMGNSARNDADGQFIRSN
LQEARWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQ
AVEMHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRA
LVKKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQ
RKQLV
Ligand information
Receptor-Ligand Complex Structure
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PDB7qwp Mechanisms of DNA opening revealed in AAA+ transcription complex structures.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		M15 L19 A22 I23 S335 H377 S379 S405 A454 R456 T457 Y461
Binding residue
(residue number reindexed from 1)		M1 L5 A8 I9 S263 H305 S307 S333 A382 R384 T385 Y389
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0016491 oxidoreductase activity
GO:0016779 nucleotidyltransferase activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qwp, PDBe:7qwp, PDBj:7qwp
PDBsum7qwp
PubMed36542713
UniProtA0A0H3H3L1

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