Structure of PDB 6m6b Chain M Binding Site BS02

Receptor Information
>6m6b Chain M (length=459) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDYLIHPEHGVGQYLGLETREVLGVKRDYLVLRYKGEGKLYLPVEQLPLL
KRHLAGRLLVLQAKRKATPGRAFPPLPEWDPLVEKGFPYELTPDQKRALE
EVLRDLESPHPMDRLVSGDVGFGKTEVALRAAHRVVGHGAQVAFLVPTTL
LAEQHGKTFRERFQGLPVRVAVLSRFTPPKEEEAILKGLAEGTVDIVIGT
HRLLQEDVRFRDLGLLIVDEEHRFGVAQKERIRELKAEVDTLYLSATPIP
RTLYSALVGLKDLSSIQTPPPGRKPIKTFLAPFDPLLVREAILFELERGG
KVFYVHDRVASIEARRRFLESLVPEARIGVVHGQMPESLIEETMLLFAEG
AYDVLLATTIIEAGLDVPEANTILIERADRLGLATLYQLRGRVGRREEEA
YAYLFHPPRLTEAAEKRLAAIADLSDLGSGHLLAERDMEIRGVGSLEVYT
ELLEEAIRK
Ligand information
Receptor-Ligand Complex Structure
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PDB6m6b Structural basis of Mfd-dependent transcription termination.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		H574 R575 G577 V578 A579 Q580 R769
Binding residue
(residue number reindexed from 1)		H222 R223 G225 V226 A227 Q228 R417
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003684 damaged DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition
GO:0006281 DNA repair
GO:0006355 regulation of DNA-templated transcription
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6m6b, PDBe:6m6b, PDBj:6m6b
PDBsum6m6b
PubMed33068413
UniProtQ72KB4

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