Structure of PDB 5wnp Chain M Binding Site BS02

Receptor Information

>5wnp Chain M (length=118) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAG

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

5wnp Chain A Residue 1857 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	5wnp 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Resolution	3.3 Å
Binding residue (original residue number in PDB)	I22 Y23
Binding residue (residue number reindexed from 1)	I21 Y22
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:5wnp, PDBe:5wnp, PDBj:5wnp
PDBsum	5wnp
PubMed	29459784
UniProt	P80377\|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)

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