Structure of PDB 3d1n Chain M Binding Site BS02

Receptor Information

>3d1n Chain M (length=150) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NMEEIREFAKNFKIRRLSLGLTQTQVGQAMTATEGPAYSQSAISRFEKLD
ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFT
PQAIEALNAYFEKNPLPTGQEITEMAKELNYDREVVRVWFSNRRQTLKNT

Ligand information

>3d1n Chain F (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ttattatttatgct

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3d1n Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
Resolution	2.51 Å
Binding residue (original residue number in PDB)	A179 S181 S183 R235 R237 R238 Q287
Binding residue (residue number reindexed from 1)	A37 S39 S41 R93 R95 R96 Q145

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:3d1n, PDBe:3d1n, PDBj:3d1n
PDBsum	3d1n
PubMed	19450691
UniProt	Q14863\|PO6F1_HUMAN POU domain, class 6, transcription factor 1 (Gene Name=POU6F1)

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